
Lee Mariault
Bioinformatics Postdoctoral Researcher
Lee Mariault
Bioinformatics Postdoctoral Researcher
MIGEVEC, IRD
Montpellier, France
CV
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Work experience
- Postdoctoral researcher at MIGEVEC (IRD), Mar. 2026 – present
- How placental malaria reshapes the transcriptional landscape of fetal cord-blood monocytes
- Integrated multi-omics workflow (scRNA-seq/multiome, spatial transcriptomics, epigenomics, proteomics, metabolomics)
- Reproducible R/Quarto analyses of a 58,000-cell multiome dataset (Seurat v5, SingleR)
- PhD student at Laboratoire Génome et Développement des Plantes (CNRS), Oct. 2022 – Nov. 2025
- Annotation-free pipeline (Python, R, Bash, SLURM) screening 418 plant and 1,081 fungal genomes
- 22 high-confidence inter-kingdom transfers, 21 of them from fungi to plants
- A plant-derived DNA transposon that invaded a powdery mildew fungus and expanded to 172 MITE copies
- First-author review in The Plant Cell (2025) and first-author preprint (2026)
- MSc intern co-supervision and teaching
- Intern at Institut Sophia Agrobiotech (INRAE / CNRS / Univ. Côte d’Azur), Jan. – June 2022
- Study of structural variants in plant-parasitic nematode genomes
- Development of a pipeline and use of tools under SLURM cluster
- Programming and scripting under Bash mainly
- Intern at Centre Méditerranéen de Médecine Moléculaire (INSERM), Feb. – July 2021
- Bioinformatics analysis of leukemic cells by single-cell RNAseq approach
- Programming and use of packages under R and Python (Seurat, SCENIC, Monocle…)
- Mini-project of drug repositioning with CMap on SARS-CoV-2 (co-first author)
Education
- PhD in Biology, Université de Perpignan Via Domitia, 2025
- MSc in Life Sciences – Biology, Computer Science & Mathematics track (with honours), Université Côte d’Azur, 2022
- BSc in Life Sciences – Bioinformatics track, Université Côte d’Azur, 2020
- TULIP Summer School on Integrative Biology and Ecology, July 2023
Skills
- Programming: Python (pandas, scikit-learn), R (tidyverse, ggplot2, Quarto), Bash, SQL
- Workflows/HPC: Nextflow, Snakemake, Docker/Singularity, Git, SLURM
- Single-cell & spatial: Seurat v5, SingleR, Monocle 3, SCENIC, Squidpy, cell2location
- Genomics/phylogenomics: BWA-MEM2, Minimap2, DIAMOND, BEDTools, MAFFT, IQ-TREE 2, AUGUSTUS
- Statistics & ML: GLM, survival analysis, Bayesian statistics, random forest
Languages
- French (native)
- English (fluent, C1 – TOEIC 955/990)
- Spanish (limited working proficiency)
Publications
- Asymmetric inter-kingdom gene transfer and a horizontal transposon invasion in a powdery mildew fungus PreprintMariault L., Lasserre E., Qian J., Hwang J-H., Kim K.D., Gibert A., Kusch S., Panstruga R., El Baidouri M.bioRxiv preprint, posted October 16, 2026
- A cryptic hybrid zone reveals the genomic basis of flower colour variation in a plant with a large and complex genome PreprintSalvado P., Gibert A., Chaib S., Raviglione D., Bertrand C., El Baidouri M., Mariault L., Llauro C., Cravero C., Dufau I., Marande W., Carpentier M-C., Martin M., Quelennec C., Gaultier P., Lewin J-M., Aymerich P., Hinoux V., Bertrand J.A.M.bioRxiv preprint, posted February 2, 2026
- Mechanisms, Detection, and Impact of Horizontal Gene Transfer in Plant Functional EvolutionLee Mariault, Camille Puginier, Jean Keller, Moaine El Baidouri, Pierre-Marc DelauxThe Plant Cell, 2025
- Identification of potentially anti-COVID-19 active drugs using the connectivity MAPRaphaël Bonnet*, Lee Mariault*, Jean-François PeyronPLOS One, 2022
Talks
- Cross-kingdom horizontal gene transfers between plant and fungal genomes: Insights from large-scale comparative genomics 🏆 Best Short Talk AwardTalk, Plant Chromosome Biology 2025, Vienna, Austria, September 2025
- Divergent Horizontal Transfer Landscapes in Liana–Tree and Plant–Fungus Interactions Revealed by Large-Scale Genome ComparisonsTalk, CNET 2025 : 25th National Congress on Transposable Elements 2025, Bordeaux, France, July 2025
- Divergent Horizontal Transfer Landscapes in Plant–Plant and Plant–Fungus Interactions Revealed by Large-Scale Genome ComparisonsTalk, Occitano-Catalan Meeting, Perpignan, France, June 2025
- Horizontal transfers in the Massane forest: the well-kept secret of lianasTalk, Symposium marking the 50th anniversary of the Massane Nature Reserve, Banyuls-sur-Mer Oceanological Observatory, France, November 2023
Teaching
- Co-supervision of an MSc internMentoring, Laboratoire Génome et Développement des Plantes (LGDP), Perpignan, Jan. – June 2025
- Computing applied to BiologyUndergraduate practical work (2nd-year BSc), 12 h, Université de Perpignan via Domitia, Biology Bachelor, 2025
- Introduction to R for scientistsUndergraduate practical work (1st-year BSc), 27 h, Université de Perpignan via Domitia, Biology Bachelor, 2025
- Statistics tutoringUndergraduate tutoring (1st-year BSc), 6 h, Université Côte d'Azur, Biology Bachelor, 2021
Outreach and service
- Author and volunteer reviewer, bioinfo-fr.net, a French-language bioinformatics blog for a general audience (2025 – present)
- IT manager of the PhD students association (UPVDoc) of the University of Perpignan (2022-2023)
- Doctoral and post-doctoral students’ representative on the Laboratory Council (2023-2025)
- Doctoral students’ representative on the doctoral school board (2023-2025)
- Scientific mediation workshop “DNA in all its states” at the science festival of Perpignan (Oct. 2022)
- DECLICS Ambassador : Scientific outreach for high school students (Nov. 2023)
- Scientific mediation workshop “PlantAdapt” at the science festival of Perpignan (Oct. 2024)